Aldol Reactions provides a comprehensive up-to-date overview of aldol reactions
including application of different metal enolates; catalytic aldol additions
catalyzed by different Lewis acids and Lewis bases; enantioselective direct
aldol additions; antibodies and enzyme catalyzed aldol additions and the recent
aggressive development of organocatalyzed aldol additions. The power of each
method is demonstrated by several applications in total synthesis of natural
products. The pros and cons of these methodologies with regard to
stereoselectivity, regioselectivity and application in total synthesis of
natural products are discussed. Great importance is set to the diverse
possibilities of the manual of aldol reaction to install required
configurations in complicated natural product synthesis.
